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Cardiology

Post-ROSC Care: What to Do After the Pulse Returns

Return of spontaneous circulation is the start of a new phase of care.

January 14, 2025

Immediate Priorities

After return of spontaneous circulation, recheck the airway, breathing, and circulation. Provide ventilation at 10 breaths per minute if the patient is not breathing adequately. Avoid hyperventilation, which can reduce blood flow to the brain.

Oxygen and Blood Pressure

Titrate oxygen to maintain saturation between 92 and 98 percent when possible, since excessive oxygen may be harmful. Monitor blood pressure, because hypotension is common after arrest. Obtain a 12-lead ECG if available, as many arrests are caused by coronary occlusion.

Prepare for Re-Arrest

Keep the AED pads on, and be ready to resume CPR if the patient loses a pulse again. Transport to a center with post-arrest care capabilities, and provide a thorough handoff including downtime, shocks delivered, and interventions.

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